ESYT1

Across TCGA patient cohorts, ESYT1 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,119 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ESYT1-associated proteins across cancer lineages are CAPN5, DAD1, and ALG5. Each is linked with ESYT1 in more than 3 cancer types. Because this analysis shows association rather than direction, both ESYT1-to-partner and partner-to-ESYT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ESYT1 versus CAPN5 in LUAD, with a Pearson correlation of -0.50.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ESYT1→partner) and Y-score (partner→ESYT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	CAPN5 →	-0.621	-0.388	<.001	<.001	3	4
UCEC	DAD1 →	-0.905	-0.730	<.001	.001	3	4
LSCC	ALG5 →	-0.456	-0.421	<.001	<.001	3	4
UCEC	LMAN1 →	-0.476	-0.629	<.001	.001	3	4
UCEC	RPN2 →	-0.614	-0.748	<.001	.003	3	4
OV	MCM2 →	+0.541	+0.560	.005	.005	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,119 associations by consensus.

ESYT1 vs CAPN5 — LUAD

Explore this scatter interactively →