ESYT1

Across TCGA patient cohorts, ESYT1 protein abundance is significantly associated with the RNA expression of many other genes, with 12,378 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ESYT1-associated genes across cancer lineages are MYL6, CD63, and ALOX5AP. Each is linked with ESYT1 in more than 5 cancer types. Because this analysis shows association rather than direction, both ESYT1-to-partner and partner-to-ESYT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ESYT1 versus MYL6 in HNSC, with a Pearson correlation of 0.27.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ESYT1→partner) and Y-score (partner→ESYT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	MYL6 →	+0.709	+0.185	.002	.008	3	6
LSCC	CD63 →	+0.641	+0.258	<.001	<.001	3	5
GBM	ALOX5AP →	+1.056	+0.251	<.001	<.001	3	5
LUAD	PCSK6 →	-0.678	-0.181	.003	.008	3	4
COAD	NDUFAF5 →	-0.453	-0.134	.002	.008	3	4
GBM	ALOX5 →	+0.971	+0.245	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,378 associations by consensus.

ESYT1 vs MYL6 — HNSC

Explore this scatter interactively →