ESS2

Across TCGA patient cohorts, ESS2 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,320 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ESS2-associated proteins across cancer lineages are TRMT2A, RANBP1, and WIZ. Each is linked with ESS2 in more than 5 cancer types. Because this analysis shows association rather than direction, both ESS2-to-partner and partner-to-ESS2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ESS2 versus TRMT2A in LSCC, with a Pearson correlation of 0.61.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ESS2→partner) and Y-score (partner→ESS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	TRMT2A →	+0.271	+0.505	<.001	<.001	3	6
OV	RANBP1 →	+0.639	+0.455	<.001	<.001	3	5
GBM	WIZ →	+0.329	+0.379	<.001	<.001	3	4
GBM	PPIL2 →	+0.393	+0.580	<.001	<.001	3	4
OV	MAPK1 →	+0.311	+0.400	.001	.002	3	4
OV	MCEE →	-0.428	-0.380	.002	.009	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,320 associations by consensus.

ESS2 vs TRMT2A — LSCC

Explore this scatter interactively →