ESS2

Across TCGA patient cohorts, ESS2 protein abundance is significantly associated with the RNA expression of many other genes, with 14,787 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ESS2-associated genes across cancer lineages are CDC45, TROAP, and ESPL1. Each is linked with ESS2 in more than 6 cancer types. Because this analysis shows association rather than direction, both ESS2-to-partner and partner-to-ESS2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ESS2 versus CDC45 in BRCA, with a Pearson correlation of 0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ESS2→partner) and Y-score (partner→ESS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CDC45 →	+1.410	+0.435	<.001	<.001	3	7
UCEC	TROAP →	+1.112	+0.188	.001	<.001	3	6
UCEC	ESPL1 →	+1.024	+0.171	.001	.001	3	6
OV	CCDC150 →	+0.704	+0.272	<.001	<.001	3	6
UCEC	BUB1 →	+1.185	+0.211	<.001	<.001	3	6
BRCA	CHEK2 →	+0.820	+0.309	<.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,787 associations by consensus.

ESS2 vs CDC45 — BRCA

Explore this scatter interactively →