Across TCGA patient cohorts, ESRRG mutation is significantly associated with the RNA expression of many other genes, with 4,695 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ESRRG-associated genes across cancer lineages are NUDT2, CEP76, and GOT1. Each is linked with ESRRG in more than 3 cancer types. Because this analysis shows association rather than direction, both ESRRG-to-partner and partner-to-ESRRG results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ESRRG→partner) and Y-score (partner→ESRRG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	NUDT2 →	+0.601	+2.192	<.001	<.001	3	4
UCEC	CEP76 →	+0.288	+2.137	.006	.009	3	3
UCEC	GOT1 →	+0.420	+2.257	<.001	<.001	3	3
UCEC	ENPP2 →	-0.680	-2.796	.001	.003	3	3
UCEC	TXNL4A →	+0.390	+1.997	<.001	<.001	3	3
SKCM	NDUFS4 →	+0.497	+2.610	.001	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,695 associations by consensus.

Exploration

ESRRG survival (RNA) · tumor vs normal (RNA) · all ESRRG data types