Across TCGA cell cohorts, ESRRG mutation is significantly associated with the RNA expression of many other genes, with 24 significant associations in total. STOMACH shows the largest number of these associations.

The most reproducible ESRRG-associated genes across cancer lineages are PIRT, SCGB1D2, and TREML1. Each is linked with ESRRG in more than 1 cancer types. Because this analysis shows association rather than direction, both ESRRG-to-partner and partner-to-ESRRG results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ESRRG→partner) and Y-score (partner→ESRRG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	PIRT →	+0.006	+4.643	<.001	.008	3	1
STOMACH	SCGB1D2 →	+1.859	+3.584	.005	.009	3	1
STOMACH	TREML1 →	+0.063	+4.044	.006	.003	3	1
STOMACH	A3GALT2 →	+0.037	+4.044	.002	.003	3	1
STOMACH	TBC1D28 →	+0.067	+3.754	<.001	.005	3	1
STOMACH	DEFB134 →	+0.124	+3.632	.002	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 24 associations by consensus.

Exploration

ESRRG survival (RNA) · tumor vs normal (RNA) · all ESRRG data types