ESRRA

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ESRRA mutation is significantly associated with the immune_cell of many other genes, with 1 significant associations in total. LUSC shows the largest number of these associations.

The most reproducible ESRRA-associated genes across cancer lineages are CD4+ Tcm. Each is linked with ESRRA in more than 1 cancer types. Because this analysis shows association rather than direction, both ESRRA-to-partner and partner-to-ESRRA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD4+ Tcm grouped by ESRRA-low versus ESRRA-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ESRRA→partner) and Y-score (partner→ESRRA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUSCCD4+ Tcm →+0.014+6.593<.001.02031
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

CD4+ Tcm by ESRRA expression — LUSC

Box plot of CD4+ Tcm in ESRRA-low vs ESRRA-high samples in LUSC.

Explore this box plot interactively →

Exploration