ESRP2

Across TCGA cell cohorts, ESRP2 mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ESRP2-associated genes across cancer lineages are OR10T2, TLE7, and CLDN17. Each is linked with ESRP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ESRP2-to-partner and partner-to-ESRP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10T2 grouped by ESRP2-low versus ESRP2-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ESRP2→partner) and Y-score (partner→ESRP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	OR10T2 →	+0.584	+4.276	.005	.007	3	1
BLOOD_Leukemia	TLE7 →	+0.032	+4.969	<.001	.003	3	1
LARGE_INTESTINE	CLDN17 →	+0.042	+3.345	.005	.007	3	1
LARGE_INTESTINE	MMP26 →	+0.032	+3.632	<.001	.003	3	1
LARGE_INTESTINE	CCR8 →	+0.159	+3.554	<.001	.007	3	1
LARGE_INTESTINE	LIPK →	+0.246	+3.554	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

OR10T2 by ESRP2 expression — BLOOD_Leukemia

Explore this box plot interactively →