ESRP1

Across TCGA cell cohorts, ESRP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,474 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible ESRP1-associated GO terms across cancer lineages are Regulation of inner ear receptor cell differentiation, Regulation of mechanoreceptor differentiation, and Cellular response to alcohol. Each is linked with ESRP1 in more than 13 cancer types. Because this analysis shows association rather than direction, both ESRP1-to-partner and partner-to-ESRP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of inner ear receptor cell differentiation grouped by ESRP1-low versus ESRP1-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ESRP1→partner) and Y-score (partner→ESRP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Regulation of inner ear receptor cell differentiation →	+1.275	+2.666	<.001	<.001	3	14
LUNG_SCLC	Regulation of mechanoreceptor differentiation →	+1.275	+2.666	<.001	<.001	3	14
LUNG_NSCLC_LUSC	Cellular response to alcohol →	+0.192	+5.235	<.001	<.001	3	11
LUNG_NSCLC_LUSC	Regulation of white fat cell proliferation →	-0.308	-4.166	<.001	<.001	3	11
LUNG_SCLC	Calcium-independent cell-cell adhesion →	+0.573	+4.694	<.001	<.001	3	11
STOMACH	Establishment of epithelial cell apical/basal polarity →	-0.243	-4.720	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,474 associations by consensus.

Regulation of inner ear receptor cell differentiation by ESRP1 expression — LUNG_SCLC

Explore this box plot interactively →