ESRG

Across TCGA patient cohorts, ESRG RNA expression is significantly associated with the protein abundance of many other proteins, with 7,976 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ESRG-associated proteins across cancer lineages are CAMSAP3, PEBP1, and PALM_T141. Each is linked with ESRG in more than 2 cancer types. Because this analysis shows association rather than direction, both ESRG-to-partner and partner-to-ESRG results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ESRG versus CAMSAP3 in GBM, with a Pearson correlation of 0.44.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ESRG→partner) and Y-score (partner→ESRG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CAMSAP3 →	+0.495	+0.108	<.001	<.001	3	3
GBM	PEBP1 →	+0.343	+0.138	<.001	.002	3	3
UCEC	PALM_T141 →	+0.702	+1.144	.002	.009	3	3
PDAC	ADD1_S59 →	+0.499	+0.050	.004	.007	3	3
LSCC	UBE2O →	+0.246	+1.075	<.001	.001	3	2
GBM	UQCRB →	+0.324	+0.113	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,976 associations by consensus.

ESRG vs CAMSAP3 — GBM

Explore this scatter interactively →