ESF1

Across TCGA patient cohorts, ESF1 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,808 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ESF1-associated proteins across cancer lineages are TRMT6, NSFL1C, and XRN2. Each is linked with ESF1 in more than 8 cancer types. Because this analysis shows association rather than direction, both ESF1-to-partner and partner-to-ESF1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ESF1 versus TRMT6 in OV, with a Pearson correlation of 0.46.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ESF1→partner) and Y-score (partner→ESF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	TRMT6 →	+0.433	+0.653	<.001	<.001	3	9
COAD	NSFL1C →	+0.347	+0.583	<.001	<.001	3	7
LSCC	XRN2 →	+0.219	+0.762	<.001	<.001	3	7
UCEC	PCNA →	+0.612	+0.559	<.001	<.001	3	6
COAD	CENPB →	+0.317	+0.623	<.001	.001	3	6
LUAD	ESF1_S153 →	+0.953	+0.571	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,808 associations by consensus.

ESF1 vs TRMT6 — OV

Explore this scatter interactively →