ESF1

Across TCGA patient cohorts, ESF1 protein abundance is significantly associated with the RNA expression of many other genes, with 22,405 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ESF1-associated genes across cancer lineages are TRMT6, MYBL2, and NOP56. Each is linked with ESF1 in more than 9 cancer types. Because this analysis shows association rather than direction, both ESF1-to-partner and partner-to-ESF1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ESF1 versus TRMT6 in LSCC, with a Pearson correlation of 0.71.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ESF1→partner) and Y-score (partner→ESF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	TRMT6 →	+0.851	+0.499	<.001	<.001	3	10
UCEC	MYBL2 →	+1.403	+0.314	<.001	<.001	3	9
UCEC	NOP56 →	+1.126	+0.479	<.001	<.001	3	9
LSCC	MCM8 →	+0.783	+0.495	<.001	<.001	3	9
BRCA	ABCA8 →	-1.130	-0.387	<.001	<.001	3	9
GBM	FLI1 →	-0.755	-0.359	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 22,405 associations by consensus.

ESF1 vs TRMT6 — LSCC

Explore this scatter interactively →