ESCO2

Across TCGA patient cohorts, ESCO2 protein abundance is significantly associated with the RNA expression of many other genes, with 5,053 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ESCO2-associated genes across cancer lineages are FAM83D, CDCA3, and ECT2. Each is linked with ESCO2 in more than 4 cancer types. Because this analysis shows association rather than direction, both ESCO2-to-partner and partner-to-ESCO2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ESCO2 versus FAM83D in LUAD, with a Pearson correlation of 0.70.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ESCO2→partner) and Y-score (partner→ESCO2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	FAM83D →	+1.364	+0.836	.001	<.001	3	5
LUAD	CDCA3 →	+1.500	+0.784	.009	.002	3	5
LSCC	ECT2 →	+1.107	+0.742	<.001	.002	3	5
LUAD	CENPF →	+1.215	+0.603	<.001	<.001	3	5
LUAD	KIF14 →	+1.449	+0.745	<.001	<.001	3	5
LUAD	HROB →	+1.359	+0.991	.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,053 associations by consensus.

ESCO2 vs FAM83D — LUAD

Explore this scatter interactively →