ESCO2

Across TCGA cell cohorts, ESCO2 RNA expression is significantly associated with the RNA expression of many other genes, with 10,688 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ESCO2-associated genes across cancer lineages are INTS9, PBK, and CDCA2. Each is linked with ESCO2 in more than 18 cancer types. Because this analysis shows association rather than direction, both ESCO2-to-partner and partner-to-ESCO2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ESCO2 versus INTS9 in BLOOD_Myeloma, with a Pearson correlation of 0.71.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ESCO2→partner) and Y-score (partner→ESCO2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	INTS9 →	+1.391	+2.133	<.001	.002	3	19
STOMACH	PBK →	+1.597	+1.403	<.001	<.001	3	19
BONE	CDCA2 →	+1.569	+1.843	.001	<.001	3	18
UPPER_AERODIGESTIVE_TRACT	GINS1 →	+1.290	+1.230	<.001	<.001	3	18
BLOOD_Myeloma	TMPO →	+1.471	+2.201	.001	<.001	3	18
BLOOD_Myeloma	DTL →	+2.075	+2.132	.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,688 associations by consensus.

ESCO2 vs INTS9 — BLOOD_Myeloma

Explore this scatter interactively →