ESCO1

Across TCGA cell cohorts, ESCO1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,349 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ESCO1-associated GO terms across cancer lineages are Peptidyl-lysine acetylation, Protein acetylation, and Vesicle coating. Each is linked with ESCO1 in more than 14 cancer types. Because this analysis shows association rather than direction, both ESCO1-to-partner and partner-to-ESCO1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Peptidyl-lysine acetylation grouped by ESCO1-low versus ESCO1-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ESCO1→partner) and Y-score (partner→ESCO1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Peptidyl-lysine acetylation →	+0.114	+0.626	<.001	<.001	2	15
OVARY	Protein acetylation →	+0.077	+0.619	<.001	.001	3	12
LUNG_SCLC	Vesicle coating →	+0.076	+0.616	<.001	<.001	3	12
URINARY_TRACT	Regulation of mitochondrial transcription →	+0.110	+0.837	<.001	<.001	3	12
URINARY_TRACT	Vesicle tethering →	+0.093	+0.946	.001	<.001	3	10
KIDNEY	Response to retinoic acid →	-0.081	-0.646	.003	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,349 associations by consensus.

Peptidyl-lysine acetylation by ESCO1 expression — BREAST

Explore this box plot interactively →