ERVMER34-1

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ERVMER34-1 mutation is significantly associated with the total protein of many other genes, with 13 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ERVMER34-1-associated genes across cancer lineages are 14-3-3_beta, INPP4B, and JNK_pT183_Y185. Each is linked with ERVMER34-1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ERVMER34-1-to-partner and partner-to-ERVMER34-1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ERVMER34-1→partner) and Y-score (partner→ERVMER34-1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCEC14-3-3_beta →-0.113-2.571.016.01131
UCECINPP4B →-0.322-2.321.032.03431
UCECJNK_pT183_Y185 →-0.190-2.999.015.03531
UCECJNK2 →+0.245+2.584.008.01131
UCECKu80 →+0.249+1.887.023.03131
UCECS6_pS240_S244 →+0.460+3.169.015.01931
Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

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