ERRFI1

Across TCGA pan-cancer cohorts, ERRFI1 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated ERRFI1 data layer compared with 27 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher ERRFI1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated ERRFI1 expression acts as an unfavorable survival marker.

PDAC, CCRCC, and LUAD are the cancer types where ERRFI1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	OS	Median	All	0.268	0.483	.002	57	view →
CCRCC	DFS	Median	II,III,IV	0.298	0.798	<.001	48	view →
LUAD	DFS	Tertile	All	0.461	0.826	.002	22	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

ERRFI1–PDAC (OS)

Open the PDAC breakdown →