ERRFI1

Across TCGA cell cohorts, ERRFI1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,880 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ERRFI1-associated GO terms across cancer lineages are Negative regulation of cardiac muscle adaptation, Negative regulation of cardiac muscle hypertrophy in response to stress, and Negative regulation of collagen metabolic process. Each is linked with ERRFI1 in more than 13 cancer types. Because this analysis shows association rather than direction, both ERRFI1-to-partner and partner-to-ERRFI1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of cardiac muscle adaptation grouped by ERRFI1-low versus ERRFI1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ERRFI1→partner) and Y-score (partner→ERRFI1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Negative regulation of cardiac muscle adaptation →	+0.289	+1.152	<.001	<.001	3	14
BONE	Negative regulation of cardiac muscle hypertrophy in response to stress →	+0.289	+1.152	<.001	<.001	3	14
LUNG_NSCLC_LUSC	Negative regulation of collagen metabolic process →	+0.226	+2.951	<.001	<.001	3	14
LUNG_SCLC	Regulation of cardiac muscle adaptation →	+0.411	+1.487	.008	.001	2	14
LUNG_SCLC	Regulation of cardiac muscle hypertrophy in response to stress →	+0.411	+1.487	.008	.001	2	14
BONE	Cellular hyperosmotic response →	+0.184	+1.698	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,880 associations by consensus.

Negative regulation of cardiac muscle adaptation by ERRFI1 expression — BONE

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