ERRFI1

Across TCGA cell cohorts, ERRFI1 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ERRFI1-associated genes across cancer lineages are BTNL2, IQCF6, and TEX53. Each is linked with ERRFI1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ERRFI1-to-partner and partner-to-ERRFI1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BTNL2 grouped by ERRFI1-low versus ERRFI1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ERRFI1→partner) and Y-score (partner→ERRFI1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	BTNL2 →	+0.081	+4.415	<.001	.007	3	1
LARGE_INTESTINE	IQCF6 →	+0.322	+4.467	<.001	.004	3	1
LARGE_INTESTINE	TEX53 →	+0.134	+4.684	<.001	.002	3	1
LARGE_INTESTINE	OR12D2 →	+0.103	+4.467	<.001	.004	3	1
LUNG_NSCLC_LUAD	CRYGD →	+0.030	+4.887	.003	.009	3	1
LUNG_NSCLC_LUAD	SPACA5B →	+0.032	+5.662	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

BTNL2 by ERRFI1 expression — LARGE_INTESTINE

Explore this box plot interactively →