Across TCGA pan-cancer cohorts, ERP27 mass-spec protein is linked to patient survival in 2 of 34 cancer types, making it a survival-associated ERP27 data layer compared with 24 for mass-spec protein and 2 for mutation status.
The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher ERP27 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated ERP27 expression acts as an unfavorable survival marker, although some lineages such as CCRCC show a favorable association.
PDAC and CCRCC are the cancer types where ERP27 mass-spec protein most reproducibly stratifies survival.