ERP27

Across TCGA patient cohorts, ERP27 mutation is significantly associated with the RNA expression of many other genes, with 781 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ERP27-associated genes across cancer lineages are RPS12P15, MIR1251, and RNU6-561P. Each is linked with ERP27 in more than 1 cancer types. Because this analysis shows association rather than direction, both ERP27-to-partner and partner-to-ERP27 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPS12P15 grouped by ERP27-low versus ERP27-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ERP27→partner) and Y-score (partner→ERP27) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RPS12P15 →	+0.148	+4.693	<.001	.007	3	2
UCEC	MIR1251 →	+0.163	+4.148	.003	.006	3	2
SKCM	RNU6-561P →	+0.220	+5.212	<.001	.002	3	2
COAD	RPL30P1 →	+0.433	+4.354	.002	.007	3	1
COAD	RPS29P6 →	+0.333	+4.893	<.001	.005	3	1
COAD	SS18L2P1 →	+1.067	+4.543	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 781 associations by consensus.

RPS12P15 by ERP27 expression — COAD

Explore this box plot interactively →