ERP27

Across TCGA cell cohorts, ERP27 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,904 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ERP27-associated GO terms across cancer lineages are Keratinocyte development, Negative regulation of actin filament polymerization, and Response to indole-3-methanol. Each is linked with ERP27 in more than 10 cancer types. Because this analysis shows association rather than direction, both ERP27-to-partner and partner-to-ERP27 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Keratinocyte development grouped by ERP27-low versus ERP27-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ERP27→partner) and Y-score (partner→ERP27) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Keratinocyte development →	-0.555	-0.755	<.001	.006	2	11
PANCREAS	Negative regulation of actin filament polymerization →	+0.161	+2.001	<.001	.005	3	9
PANCREAS	Response to indole-3-methanol →	+0.199	+2.254	<.001	<.001	3	9
STOMACH	Cellular response to indole-3-methanol →	+0.230	+1.800	<.001	.002	3	9
OESOPHAGUS	Rho protein signal transduction →	+0.136	+3.548	<.001	.001	3	9
URINARY_TRACT	Regulation of heart rate by cardiac conduction →	+0.199	+3.467	.004	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,904 associations by consensus.

Keratinocyte development by ERP27 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →