ERP27

Across TCGA cell cohorts, ERP27 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ERP27-associated genes across cancer lineages are SPATA31E1, STH, and CD300E. Each is linked with ERP27 in more than 1 cancer types. Because this analysis shows association rather than direction, both ERP27-to-partner and partner-to-ERP27 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SPATA31E1 grouped by ERP27-low versus ERP27-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ERP27→partner) and Y-score (partner→ERP27) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	SPATA31E1 →	+0.166	+4.906	<.001	.006	3	1
OESOPHAGUS	STH →	+0.076	+4.906	<.001	.006	3	1
OVARY	CD300E →	+0.046	+5.807	<.001	.001	3	1
LUNG_NSCLC_LUAD	ADAM30 →	+0.006	+4.212	.008	.007	3	1
LARGE_INTESTINE	ARGFX →	+0.012	+4.437	<.001	.004	3	1
LARGE_INTESTINE	PRR27 →	+0.193	+4.054	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

SPATA31E1 by ERP27 expression — OESOPHAGUS

Explore this box plot interactively →