ERO1B

Across TCGA patient cohorts, ERO1B mutation is significantly associated with the RNA expression of many other genes, with 2,179 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ERO1B-associated genes across cancer lineages are TTTY7, SNORD116-23, and ATP5PDP1. Each is linked with ERO1B in more than 1 cancer types. Because this analysis shows association rather than direction, both ERO1B-to-partner and partner-to-ERO1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TTTY7 grouped by ERO1B-low versus ERO1B-high in ESCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ERO1B→partner) and Y-score (partner→ERO1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	TTTY7 →	+0.052	+6.285	<.001	.001	3	2
UCEC	SNORD116-23 →	+0.612	+2.225	<.001	<.001	3	2
UCEC	ATP5PDP1 →	+0.231	+2.291	<.001	<.001	3	2
UCEC	RNA5SP412 →	+0.556	+1.774	<.001	.009	3	2
ESCA	MTCYBP2 →	+0.283	+5.068	<.001	.008	3	1
UCEC	ABALON →	+0.493	+1.880	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,179 associations by consensus.

TTTY7 by ERO1B expression — ESCA

Explore this box plot interactively →