Across TCGA patient cohorts, ERO1A protein abundance is significantly associated with the RNA expression of many other genes, with 16,732 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ERO1A-associated genes across cancer lineages are EGLN3, FRAT1, and CXCL8. Each is linked with ERO1A in more than 7 cancer types. Because this analysis shows association rather than direction, both ERO1A-to-partner and partner-to-ERO1A results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ERO1A→partner) and Y-score (partner→ERO1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	EGLN3 →	+1.464	+0.664	<.001	<.001	3	8
GBM	FRAT1 →	-0.658	-0.562	<.001	.001	3	8
GBM	CXCL8 →	+1.992	+0.451	<.001	<.001	3	8
COAD	SLC2A1 →	+1.321	+0.501	<.001	<.001	3	8
BRCA	TMSB10 →	+1.005	+0.548	<.001	<.001	3	8
GBM	CA9 →	+1.947	+0.755	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,732 associations by consensus.

Exploration

ERO1A survival (RNA) · tumor vs normal (RNA) · all ERO1A data types