ERN2

Across TCGA patient cohorts, ERN2 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,533 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible ERN2-associated proteins across cancer lineages are AGR2, STARD10, and GCC2. Each is linked with ERN2 in more than 5 cancer types. Because this analysis shows association rather than direction, both ERN2-to-partner and partner-to-ERN2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ERN2 versus AGR2 in LSCC, with a Pearson correlation of 0.59.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ERN2→partner) and Y-score (partner→ERN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	AGR2 →	+0.792	+1.064	<.001	<.001	3	6
LUAD	STARD10 →	+0.457	+1.227	<.001	.005	3	5
COAD	GCC2 →	+0.325	+1.121	<.001	<.001	3	5
HNSC	HID1 →	+0.583	+1.039	<.001	<.001	3	5
PDAC	CAPN5 →	+0.603	+1.138	<.001	<.001	3	5
COAD	AGR3 →	+1.086	+0.885	<.001	.005	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,533 associations by consensus.

ERN2 vs AGR2 — LSCC

Explore this scatter interactively →