ERN2

Across TCGA patient cohorts, ERN2 protein abundance is significantly associated with the RNA expression of many other genes, with 5,805 significant associations in total. COAD shows the largest number of these associations.

The most reproducible ERN2-associated genes across cancer lineages are AGR2, MLPH, and MUC5B. Each is linked with ERN2 in more than 4 cancer types. Because this analysis shows association rather than direction, both ERN2-to-partner and partner-to-ERN2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ERN2 versus AGR2 in UCEC, with a Pearson correlation of 0.50.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ERN2→partner) and Y-score (partner→ERN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	AGR2 →	+2.414	+1.912	.001	<.001	3	5
UCEC	MLPH →	+1.445	+1.547	<.001	<.001	3	4
UCEC	MUC5B →	+3.252	+1.660	<.001	<.001	3	4
PDAC	TFF1 →	+3.324	+0.866	<.001	<.001	3	4
LUAD	SLC44A4 →	+1.621	+0.951	.004	.001	3	4
UCEC	CREB3L1 →	+2.239	+1.327	<.001	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,805 associations by consensus.

ERN2 vs AGR2 — UCEC

Explore this scatter interactively →