ERMP1

Across TCGA patient cohorts, ERMP1 mutation is significantly associated with the total protein of many other genes, with 46 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ERMP1-associated genes across cancer lineages are p53, Akt_pT308, and CD31. Each is linked with ERMP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ERMP1-to-partner and partner-to-ERMP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, p53 grouped by ERMP1-low versus ERMP1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ERMP1→partner) and Y-score (partner→ERMP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	p53 →	-0.304	-2.115	.013	.016	3	2
UCEC	Akt_pT308 →	+0.438	+1.807	.029	.024	3	2
UCEC	CD31 →	-0.144	-2.237	.002	.001	3	2
UCEC	4E-BP1 →	+0.241	+2.115	.005	.016	3	2
UCEC	14-3-3_beta →	-0.091	-1.880	.004	.014	3	1
UCEC	EGFR_pY1068 →	-0.217	-1.289	.006	.023	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 46 associations by consensus.

p53 by ERMP1 expression — UCEC

Explore this box plot interactively →