ERMP1

Across TCGA cell cohorts, ERMP1 mutation is significantly associated with the RNA expression of many other genes, with 42 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ERMP1-associated genes across cancer lineages are OR8G1, OR8D2, and PGK2. Each is linked with ERMP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ERMP1-to-partner and partner-to-ERMP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR8G1 grouped by ERMP1-low versus ERMP1-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ERMP1→partner) and Y-score (partner→ERMP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	OR8G1 →	+0.095	+5.643	<.001	.002	3	2
BLOOD_Lymphoma	OR8D2 →	+0.105	+4.867	<.001	.009	3	2
SKIN	PGK2 →	+0.034	+4.415	<.001	.007	3	2
LUNG_SCLC	IL3 →	+0.055	+5.029	<.001	.006	3	1
LUNG_SCLC	PRAMEF10 →	+1.180	+5.643	<.001	.002	3	1
LUNG_SCLC	PRAMEF17 →	+0.013	+5.643	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 42 associations by consensus.

OR8G1 by ERMP1 expression — BLOOD_Lymphoma

Explore this box plot interactively →