ERMAP

Across TCGA patient cohorts, ERMAP protein abundance is significantly associated with the RNA expression of many other genes, with 1,283 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ERMAP-associated genes across cancer lineages are HBA2, HEMGN, and PPBP. Each is linked with ERMAP in more than 3 cancer types. Because this analysis shows association rather than direction, both ERMAP-to-partner and partner-to-ERMAP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ERMAP versus HBA2 in CCRCC, with a Pearson correlation of 0.84.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ERMAP→partner) and Y-score (partner→ERMAP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	HBA2 →	+3.233	+0.738	.001	.002	3	4
CCRCC	HEMGN →	+2.371	+1.189	<.001	<.001	3	3
CCRCC	PPBP →	+2.853	+1.052	<.001	<.001	3	3
CCRCC	HBA1 →	+3.036	+0.738	.002	.002	3	3
CCRCC	HBB →	+3.316	+0.738	<.001	.002	3	3
CCRCC	HMOX1 →	+1.536	+1.086	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,283 associations by consensus.

ERMAP vs HBA2 — CCRCC

Explore this scatter interactively →