ERLIN2

Across TCGA patient cohorts, ERLIN2 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,032 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible ERLIN2-associated proteins across cancer lineages are PLPBP, NSD3, and BAG4. Each is linked with ERLIN2 in more than 7 cancer types. Because this analysis shows association rather than direction, both ERLIN2-to-partner and partner-to-ERLIN2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ERLIN2 versus PLPBP in BRCA, with a Pearson correlation of 0.79.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ERLIN2→partner) and Y-score (partner→ERLIN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PLPBP →	+0.474	+1.123	<.001	<.001	3	8
BRCA	NSD3 →	+0.670	+1.067	<.001	<.001	3	7
BRCA	BAG4 →	+0.698	+1.007	<.001	<.001	3	7
CCRCC	RAB11FIP1 →	+0.374	+0.383	<.001	.005	3	6
BRCA	POLB →	+0.447	+0.718	<.001	<.001	3	6
LSCC	DDHD2 →	+0.520	+0.893	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,032 associations by consensus.

ERLIN2 vs PLPBP — BRCA

Explore this scatter interactively →