ERLEC1

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ERLEC1 mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ERLEC1-associated genes across cancer lineages are Adipocytes and pDC. Each is linked with ERLEC1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ERLEC1-to-partner and partner-to-ERLEC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Adipocytes grouped by ERLEC1-low versus ERLEC1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ERLEC1→partner) and Y-score (partner→ERLEC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMAdipocytes →+0.035+2.593.012.03531
UCECpDC →+0.065+2.202.003.03331
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Adipocytes by ERLEC1 expression — SKCM

Box plot of Adipocytes in ERLEC1-low vs ERLEC1-high samples in SKCM.

Explore this box plot interactively →

Exploration