ERLEC1

Across TCGA cell cohorts, ERLEC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,205 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ERLEC1-associated GO terms across cancer lineages are Endoplasmic reticulum to cytosol transport, Retrograde protein transport, ER to cytosol, and Endoplasmic reticulum to Golgi vesicle-mediated transport. Each is linked with ERLEC1 in more than 18 cancer types. Because this analysis shows association rather than direction, both ERLEC1-to-partner and partner-to-ERLEC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endoplasmic reticulum to cytosol transport grouped by ERLEC1-low versus ERLEC1-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ERLEC1→partner) and Y-score (partner→ERLEC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Endoplasmic reticulum to cytosol transport →	+0.140	+0.801	<.001	<.001	3	19
STOMACH	Retrograde protein transport, ER to cytosol →	+0.140	+0.801	<.001	<.001	3	19
STOMACH	Endoplasmic reticulum to Golgi vesicle-mediated transport →	+0.102	+0.791	<.001	<.001	3	19
STOMACH	Protein exit from endoplasmic reticulum →	+0.133	+0.848	<.001	<.001	3	18
STOMACH	Golgi vesicle transport →	+0.085	+0.801	<.001	<.001	3	18
SOFT_TISSUE	Endoplasmic reticulum mannose trimming →	+0.121	+0.795	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,205 associations by consensus.

Endoplasmic reticulum to cytosol transport by ERLEC1 expression — STOMACH

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