ERICH6B

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ERICH6B mutation is significantly associated with the RNA expression of many other genes, with 3,469 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ERICH6B-associated genes across cancer lineages are RNA5SP410, RNU6-1213P, and RNU6-1036P. Each is linked with ERICH6B in more than 1 cancer types. Because this analysis shows association rather than direction, both ERICH6B-to-partner and partner-to-ERICH6B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP410 grouped by ERICH6B-low versus ERICH6B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ERICH6B→partner) and Y-score (partner→ERICH6B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRNA5SP410 →+0.495+1.467<.001.00732
COADRNU6-1213P →+0.814+7.156<.001<.00132
COADRNU6-1036P →+1.177+3.951<.001.00532
COADNFU1P1 →+0.414+4.219<.001.00332
BRCAMIR6754 →+0.558+5.883<.001.00331
CESCH4P1 →+0.183+5.010<.001.00931
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,469 associations by consensus.

RNA5SP410 by ERICH6B expression — UCEC

Box plot of RNA5SP410 in ERICH6B-low vs ERICH6B-high samples in UCEC.

Explore this box plot interactively →

Exploration