ERICH6B

Across TCGA patient cohorts, ERICH6B mutation is significantly associated with the total protein of many other genes, with 31 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ERICH6B-associated genes across cancer lineages are 14-3-3_beta, Fibronectin, and Heregulin. Each is linked with ERICH6B in more than 1 cancer types. Because this analysis shows association rather than direction, both ERICH6B-to-partner and partner-to-ERICH6B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 14-3-3_beta grouped by ERICH6B-low versus ERICH6B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ERICH6B→partner) and Y-score (partner→ERICH6B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	14-3-3_beta →	-0.079	-1.673	.014	.040	3	1
UCEC	Fibronectin →	-0.281	-3.446	.008	.005	3	1
UCEC	Heregulin →	-0.112	-2.000	.005	<.001	3	1
UCEC	JNK2 →	+0.263	+2.321	<.001	<.001	3	1
UCEC	MEK1 →	+0.463	+2.000	<.001	<.001	3	1
UCEC	Mre11 →	-0.077	-1.716	.005	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 31 associations by consensus.

14-3-3_beta by ERICH6B expression — UCEC

Explore this box plot interactively →