Across TCGA patient cohorts, ERICH4 mutation is significantly associated with the immune_cell of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ERICH4-associated genes across cancer lineages are CD8+ T-cells, CD8+ Tcm, and Macrophages. Each is linked with ERICH4 in more than 1 cancer types. Because this analysis shows association rather than direction, both ERICH4-to-partner and partner-to-ERICH4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ERICH4→partner) and Y-score (partner→ERICH4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CD8+ T-cells →	+0.029	+3.845	<.001	<.001	3	1
UCEC	CD8+ Tcm →	+0.056	+3.198	<.001	.009	3	1
UCEC	Macrophages →	+0.047	+3.072	<.001	.005	3	1
UCEC	Macrophages M1 →	+0.047	+2.818	<.001	.037	1	1
UCEC	Macrophages M2 →	+0.018	+2.925	.005	.031	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Exploration

ERICH4 survival (RNA) · tumor vs normal (RNA) · all ERICH4 data types