ERICH1

Across TCGA pan-cancer cohorts, ERICH1 Mutation is linked to patient survival in 5 of 34 cancer types, making it a survival-associated ERICH1 data layer compared with 23 for mass-spec protein and 3 for mass-spec protein.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher ERICH1 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated ERICH1 expression acts as an unfavorable survival marker, although some lineages such as STAD show a favorable association.

ACC, KIRC, and STAD are the cancer types where ERICH1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Median	All	0.010	0.667	<.001	45	view →
KIRC	OS	Median	All	0.062	0.874	<.001	36	view →
STAD	DFS	Median	All	1.000	0.384	.029	9	view →
PRAD	DFS	Median	All	0.085	0.774	<.001	6	view →
COAD	OS	Median	All	0.176	0.678	.011	6	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

ERICH1–ACC (DFS)

Open the ACC breakdown →