Across TCGA patient cohorts, ERI2 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,483 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ERI2-associated proteins across cancer lineages are DCTPP1, NFATC2IP, and PARN. Each is linked with ERI2 in more than 8 cancer types. Because this analysis shows association rather than direction, both ERI2-to-partner and partner-to-ERI2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ERI2→partner) and Y-score (partner→ERI2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	DCTPP1 →	+0.544	+0.381	<.001	<.001	3	9
LSCC	NFATC2IP →	+0.302	+0.433	<.001	<.001	3	6
OV	PARN →	+0.276	+0.453	.002	.003	3	6
LSCC	POLR3E →	+0.298	+0.527	<.001	<.001	3	6
BRCA	LCMT1 →	+0.541	+0.877	<.001	<.001	3	6
LSCC	GTF3C1 →	+0.266	+0.457	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,483 associations by consensus.

Exploration

ERI2 survival (RNA) · tumor vs normal (RNA) · all ERI2 data types