Across TCGA cell cohorts, ERI2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,007 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible ERI2-associated GO terms across cancer lineages are Exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), Symbiont-mediated disruption of host cell PML body, and Double-strand break repair via nonhomologous end joining. Each is linked with ERI2 in more than 14 cancer types. Because this analysis shows association rather than direction, both ERI2-to-partner and partner-to-ERI2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ERI2→partner) and Y-score (partner→ERI2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.114	+0.862	.001	.003	3	15
OVARY	Symbiont-mediated disruption of host cell PML body →	+0.128	+0.917	<.001	<.001	3	14
CNS	Double-strand break repair via nonhomologous end joining →	+0.058	+0.730	<.001	<.001	3	13
SOFT_TISSUE	Positive regulation of chromosome condensation →	+0.219	+0.947	<.001	<.001	3	12
SOFT_TISSUE	RNA 3'-end processing →	+0.088	+1.034	<.001	<.001	3	12
SOFT_TISSUE	DNA biosynthetic process →	+0.068	+1.133	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,007 associations by consensus.

Exploration

ERI2 survival (RNA) · tumor vs normal (RNA) · all ERI2 data types