ERI1

Across TCGA pan-cancer cohorts, ERI1 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated ERI1 data layer compared with 25 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher ERI1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated ERI1 expression acts as an unfavorable survival marker, although some lineages such as HNSC show a favorable association.

PDAC, HNSC, and CCRCC are the cancer types where ERI1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	DFS	Median	IV	0.214	0.785	.006	12	view →
HNSC	OS	Tertile	II,III,IV	0.806	0.583	.031	6	view →
CCRCC	OS	Median	II,III,IV	0.454	1.000	.014	6	view →
LUAD	OS	Tertile	All	0.675	0.876	.033	1	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

ERI1–PDAC (DFS)

Open the PDAC breakdown →