ERI1

Across TCGA patient cohorts, ERI1 protein abundance is significantly associated with the RNA expression of many other genes, with 16,785 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ERI1-associated genes across cancer lineages are ESCO2, SH2D4A, and KCTD9. Each is linked with ERI1 in more than 8 cancer types. Because this analysis shows association rather than direction, both ERI1-to-partner and partner-to-ERI1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ERI1 versus ESCO2 in COAD, with a Pearson correlation of 0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ERI1→partner) and Y-score (partner→ERI1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	ESCO2 →	+0.714	+0.381	<.001	<.001	3	9
COAD	SH2D4A →	+0.810	+0.437	<.001	<.001	3	8
COAD	KCTD9 →	+0.794	+0.446	<.001	<.001	3	8
OV	CHMP7 →	+0.551	+0.410	<.001	<.001	3	8
BRCA	CDCA2 →	+1.152	+0.481	<.001	<.001	3	8
COAD	CNOT7 →	+0.643	+0.430	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,785 associations by consensus.

ERI1 vs ESCO2 — COAD

Explore this scatter interactively →