ERI1

Across TCGA patient cohorts, ERI1 mutation is significantly associated with the RNA expression of many other genes, with 1,235 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ERI1-associated genes across cancer lineages are RPL23AP90, RNU6-1213P, and MIR487B. Each is linked with ERI1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ERI1-to-partner and partner-to-ERI1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPL23AP90 grouped by ERI1-low versus ERI1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ERI1→partner) and Y-score (partner→ERI1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RPL23AP90 →	+0.358	+3.811	<.001	.003	3	2
UCEC	RNU6-1213P →	+0.255	+4.002	<.001	.001	3	2
COAD	MIR487B →	+0.357	+7.741	<.001	.009	3	2
SKCM	APCS →	+0.694	+3.668	<.001	.002	3	1
UCEC	MAP3K4-AS1 →	+0.766	+3.343	.002	.005	3	1
UCEC	RBAK-RBAKDN →	+0.098	+2.267	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,235 associations by consensus.

RPL23AP90 by ERI1 expression — SKCM

Explore this box plot interactively →