ERH

Across TCGA cell cohorts, ERH RNA expression is significantly associated with the go_rna of many other GO terms, with 4,055 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ERH-associated GO terms across cancer lineages are Immunoglobulin heavy chain V-D-J recombination, U1 snRNA 3'-end processing, and U5 snRNA 3'-end processing. Each is linked with ERH in more than 12 cancer types. Because this analysis shows association rather than direction, both ERH-to-partner and partner-to-ERH results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Immunoglobulin heavy chain V-D-J recombination grouped by ERH-low versus ERH-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ERH→partner) and Y-score (partner→ERH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Immunoglobulin heavy chain V-D-J recombination →	+0.179	+0.468	<.001	<.001	3	13
KIDNEY	U1 snRNA 3'-end processing →	+0.106	+0.779	.001	<.001	3	12
KIDNEY	U5 snRNA 3'-end processing →	+0.106	+0.779	.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	DNA-templated DNA replication →	+0.118	+0.901	.001	.007	3	12
SOFT_TISSUE	DNA replication initiation →	+0.175	+0.538	<.001	<.001	3	12
SOFT_TISSUE	Double-strand break repair →	+0.064	+0.583	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,055 associations by consensus.

Immunoglobulin heavy chain V-D-J recombination by ERH expression — SOFT_TISSUE

Explore this box plot interactively →