ERGIC2

Across TCGA patient cohorts, ERGIC2 protein abundance is significantly associated with the RNA expression of many other genes, with 11,754 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible ERGIC2-associated genes across cancer lineages are TNXB, PALM, and PPP2R5A. Each is linked with ERGIC2 in more than 4 cancer types. Because this analysis shows association rather than direction, both ERGIC2-to-partner and partner-to-ERGIC2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ERGIC2 versus TNXB in UCEC, with a Pearson correlation of -0.28.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ERGIC2→partner) and Y-score (partner→ERGIC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TNXB →	-0.917	-0.414	.001	<.001	3	5
BRCA	PALM →	-0.960	-0.394	<.001	<.001	3	5
LUAD	PPP2R5A →	-0.523	-0.311	.003	.003	3	5
CCRCC	GARNL3 →	-0.547	-0.382	<.001	<.001	3	5
HNSC	ITGA7 →	-0.752	-0.164	<.001	.004	3	4
BRCA	ARRB1 →	-0.719	-0.423	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,754 associations by consensus.

ERGIC2 vs TNXB — UCEC

Explore this scatter interactively →