ERGIC2

Across TCGA cell cohorts, ERGIC2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,683 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible ERGIC2-associated GO terms across cancer lineages are Regulation of endoplasmic reticulum tubular network organization, Vesicle fusion with Golgi apparatus, and Positive regulation of endoplasmic reticulum tubular network organization. Each is linked with ERGIC2 in more than 11 cancer types. Because this analysis shows association rather than direction, both ERGIC2-to-partner and partner-to-ERGIC2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of endoplasmic reticulum tubular network organization grouped by ERGIC2-low versus ERGIC2-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ERGIC2→partner) and Y-score (partner→ERGIC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Regulation of endoplasmic reticulum tubular network organization →	+0.091	+0.809	.001	.002	3	12
BONE	Vesicle fusion with Golgi apparatus →	+0.111	+0.880	.003	.005	3	12
URINARY_TRACT	Positive regulation of endoplasmic reticulum tubular network organization →	+0.126	+0.941	<.001	<.001	3	11
CNS	Zinc ion import into Golgi lumen →	+0.082	+0.454	<.001	<.001	3	10
LIVER	Positive regulation of translational initiation →	+0.113	+0.600	<.001	.004	3	10
STOMACH	Protein localization to nuclear envelope →	+0.112	+1.076	<.001	.001	2	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,683 associations by consensus.

Regulation of endoplasmic reticulum tubular network organization by ERGIC2 expression — URINARY_TRACT

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