ERG28

Across TCGA pan-cancer cohorts, ERG28 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated ERG28 data layer compared with 22 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher ERG28 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated ERG28 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and GBM show a favorable association.

CCRCC, GBM, and HNSC are the cancer types where ERG28 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Median	All	0.910	0.766	.009	20	view →
GBM	OS	Tertile	All	0.452	0.261	.012	11	view →
HNSC	DFS	Quartile	II,III,IV	0.829	0.585	.034	6	view →
LSCC	OS	Quartile	All	1.000	0.599	.027	2	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

ERG28–CCRCC (OS)

Open the CCRCC breakdown →