ERFL

Across TCGA patient cohorts, ERFL RNA expression is significantly associated with the protein abundance of many other proteins, with 10,323 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible ERFL-associated proteins across cancer lineages are DOCK2, NCKAP1L, and ARHGAP25. Each is linked with ERFL in more than 4 cancer types. Because this analysis shows association rather than direction, both ERFL-to-partner and partner-to-ERFL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ERFL versus DOCK2 in BRCA, with a Pearson correlation of 0.27.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ERFL→partner) and Y-score (partner→ERFL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	DOCK2 →	+0.577	+0.359	<.001	.005	3	5
LSCC	NCKAP1L →	+0.507	+0.367	<.001	<.001	3	4
LSCC	ARHGAP25 →	+0.588	+0.388	<.001	<.001	3	4
HNSC	PLEKHO2 →	+0.297	+0.465	.001	.002	3	4
LSCC	SEPTIN1 →	+0.856	+0.371	<.001	<.001	3	4
LSCC	IL16 →	+0.627	+0.330	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,323 associations by consensus.

ERFL vs DOCK2 — BRCA

Explore this scatter interactively →