ERCC6L2

Across TCGA patient cohorts, ERCC6L2 RNA expression is significantly associated with the protein abundance of many other proteins, with 19,095 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ERCC6L2-associated proteins across cancer lineages are PHF2, RAD23B, and EIF5B_S1168. Each is linked with ERCC6L2 in more than 5 cancer types. Because this analysis shows association rather than direction, both ERCC6L2-to-partner and partner-to-ERCC6L2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ERCC6L2 versus PHF2 in OV, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ERCC6L2→partner) and Y-score (partner→ERCC6L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PHF2 →	+0.430	+0.678	<.001	<.001	3	6
BRCA	RAD23B →	+0.266	+0.462	<.001	.001	3	6
PDAC	EIF5B_S1168 →	-0.466	-0.429	<.001	<.001	3	6
GBM	BRD3 →	+0.333	+0.403	<.001	<.001	3	5
BRCA	CALR →	-0.260	-0.337	<.001	<.001	3	5
CCRCC	CKAP4_S26 →	-0.658	-0.317	.006	.009	2	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,095 associations by consensus.

ERCC6L2 vs PHF2 — OV

Explore this scatter interactively →