Across TCGA patient cohorts, ERCC6L protein abundance is significantly associated with the RNA expression of many other genes, with 14,307 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ERCC6L-associated genes across cancer lineages are PRC1-AS1, MCM5, and CDKN3. Each is linked with ERCC6L in more than 5 cancer types. Because this analysis shows association rather than direction, both ERCC6L-to-partner and partner-to-ERCC6L results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ERCC6L→partner) and Y-score (partner→ERCC6L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PRC1-AS1 →	+0.709	+0.802	<.001	<.001	3	6
UCEC	MCM5 →	+1.092	+0.470	<.001	<.001	3	6
LUAD	CDKN3 →	+1.152	+0.575	<.001	<.001	3	6
HNSC	VRK1 →	+0.805	+0.299	<.001	<.001	3	6
LUAD	GINS1 →	+1.000	+0.597	<.001	<.001	3	6
LUAD	MYBL2 →	+1.601	+0.643	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,307 associations by consensus.

Exploration

ERCC6L survival (RNA) · tumor vs normal (RNA) · all ERCC6L data types