Across TCGA patient cohorts, ERCC6 protein abundance is significantly associated with the protein abundance of many other proteins, with 11,804 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ERCC6-associated proteins across cancer lineages are MYDGF, CABIN1, and CEP170_S958. Each is linked with ERCC6 in more than 3 cancer types. Because this analysis shows association rather than direction, both ERCC6-to-partner and partner-to-ERCC6 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ERCC6→partner) and Y-score (partner→ERCC6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	MYDGF →	-0.428	-0.433	<.001	<.001	3	4
OV	CABIN1 →	+0.513	+0.456	<.001	<.001	3	3
OV	CEP170_S958 →	-1.247	-0.560	<.001	<.001	3	3
CCRCC	CTNND1_S847 →	+0.777	+0.434	<.001	<.001	3	3
CCRCC	TM9SF3 →	-0.263	-0.489	<.001	<.001	3	3
CCRCC	TRIM25 →	-0.201	-0.413	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,804 associations by consensus.

Exploration

ERCC6 survival (RNA) · tumor vs normal (RNA) · all ERCC6 data types